Knowledge about adverse drug reactions following noncompliance among Tuberculosis clients at Bwaila hospital in Lilongwe District.

Statistics have shown significant prevalence of adverse drug reactions with an estimated 500,000 cases of multi-drug resistant tuberculosis (MDR-TB) arising every year among both new and previously treated tuberculosis clients, with much higher prevalence among previously treated client. Extensively...

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Bibliographic Details
Main Author: Kamanga, McDonald
Format: Other
Language:other
Published: Kamuzu University of Health Sciences 2022
Online Access:http://nkhokwe.kuhes.ac.mw/handle/20.500.12845/368
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Summary:Statistics have shown significant prevalence of adverse drug reactions with an estimated 500,000 cases of multi-drug resistant tuberculosis (MDR-TB) arising every year among both new and previously treated tuberculosis clients, with much higher prevalence among previously treated client. Extensively drug resistant tuberculosis has also been reported from many countries. In 2007, the results of a cohort study done by WHO in Malawi showed that the number of deaths among patients with MDR-TB was very high. Out of 82 MDR-TB patients who registered, 41 patients (50%) died. Only eight (20%) of the remaining cases were on treatment as of December 2007, while the rest defaulted. In 2005, among 164 TB patients, 31 patients (19%) developed MDR-TB. This is an indication that the problem of adverse drug reactions in Malawi is there only that most patients are not known to carry the drug resistant strains because there are 1 no laboratory equipment to diagnose MDR-TB and XDR-TB. This study which is descriptive in nature will address the knowledge on adverse drug reactions following noncompliance among TB clients. The study will establish the relationship between noncompliance and clients' knowledge about tuberculosis and adverse drug reactions following noncompliance; the utilization of medications among TB clients and barriers that may hinder 1 them from accessing medications; the accessibility of information on adverse reactions following drug noncompliance, and problems that TB clients face when taking TB drug. A sample of 10 patients with TB infection, new or re-treated, will be recruited from Bwaila Hospital. The sample size of 1 0 has been chosen because it is the appropriate number in qualitative study since the researcher wants to obtain rich information from the subjects. Data will be collected through interviews using an interview guide composed of semi-structured questions designed by the researcher. Microsoft excel software (Epi info. Statistical Package) will be used to analyse descriptive data. Responses from open ended questions will be coded before analysis. The findings of this study will address the adverse drug reactions following noncompliance and will improve health services in TB clients.